Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.8K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.8K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

69.5K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
69.5K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

2.7K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
2.7K
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

922
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
922
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.2K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.2K
Sympathetic Activation01:16

Sympathetic Activation

8.1K
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical Students' Reflections on Cultural Uncertainty During an International Global Health Program: A Qualitative Study.

Medical science educator·2026
Same author

Psychiatric comorbidities, postoperative pain, and healthcare utilization after ankle repair: A propensity-matched analysis.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons·2026
Same author

A novel audit methodology to improve detection of planning and delivery errors in passive motion management.

Physics and imaging in radiation oncology·2026
Same author

A Multicenter Study of Noninvasive Wireless Assessment of Cerebrospinal Fluid Shunt Function in Hydrocephalus Patients.

Neurosurgery·2025
Same author

Hyponatremia and Acute Kidney Injury Following Spine Surgery.

Journal of surgical orthopaedic advances·2025
Same author

Firing properties of muscle spindle afferents in the intrinsic foot muscles and tactile afferents from the sole of the foot during upright stance.

Experimental physiology·2025

Related Experiment Video

Updated: Mar 21, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.5K

Cozen's phenomenon revisited.

Alex Burton1, William Hennrikus

  • 1Department of Orthopaedics, Penn State College of Medicine, Hershey, Pennsylvania, USA.

Journal of Pediatric Orthopedics. Part B
|May 17, 2016
PubMed
Summary

This study evaluated Cozen

Area of Science:

  • Pediatric Orthopedics
  • Pediatric Trauma
  • Pediatric Fracture Management

Background:

  • Cozen's fracture is a common injury in children.
  • Previous treatment methods for Cozen's fracture have varying outcomes.
  • Effectiveness of cast treatment with a varus mold for Cozen's fracture is not well-documented.

Purpose of the Study:

  • To assess the effectiveness of treating pediatric Cozen's fractures using a long leg cast with the knee in extension and a varus mold.
  • To determine the rate of valgus deformity development following this specific treatment protocol.

Main Methods:

  • Retrospective review of 14 pediatric patients treated for Cozen's fracture.
  • Treatment involved a long leg cast with the knee extended and a varus mold.

More Related Videos

Cortisol Measurement in Koala Phascolarctos cinereus Fur
09:11

Cortisol Measurement in Koala Phascolarctos cinereus Fur

Published on: August 23, 2019

11.2K
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

23.6K

Related Experiment Videos

Last Updated: Mar 21, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.5K
Cortisol Measurement in Koala Phascolarctos cinereus Fur
09:11

Cortisol Measurement in Koala Phascolarctos cinereus Fur

Published on: August 23, 2019

11.2K
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

23.6K
  • Data collected included patient age, time to valgus deformity, and follow-up duration.
  • Main Results:

    • The study included 14 children with an average age of 3 years.
    • The average time to developing valgus deformity was 8.8 months.
    • 50% of patients developed a 5° valgus deformity, which was minimized compared to prior literature.

    Conclusions:

    • Treatment of Cozen's fracture with a long leg cast in extension and a varus mold appears to minimize valgus deformity.
    • This method offers a potentially effective conservative management strategy for pediatric Cozen's fractures.
    • Further research is warranted to confirm these findings and compare with other treatment modalities.