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Related Concept Videos

Feedback Inhibition

Feedback Inhibition

Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!

Feedback Loops

Feedback Loops

In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.

Internal Receptors

Internal Receptors

Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.

Cross-reactivity

Cross-reactivity

Proofreading

Proofreading

What are Second Messengers?

What are Second Messengers?

Because many receptor binding ligands are hydrophilic, they do not cross the cell membrane and thus their message must be relayed to a second messenger on the inside. There are several second messenger pathways, each with their own way of relaying information. G-protein coupled receptors can activate both phosphoinositol and cyclic AMP (cAMP) second messenger pathways. The phosphoinositol path is active when the receptor induces phospholipase C to hydrolyze the phospholipid,...

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Related Experiment Video

Updated: Mar 21, 2026

Studying Aggression in Drosophila fruit flies

Studying Aggression in Drosophila fruit flies

Published on: February 25, 2007

The authors reply

Viranuj Sueblinvong¹, Daniel W Johnson, Gary L Weinstein

¹Division of Pulmonary, Department of Medicine, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, GA; Division of Critical Care, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Texas Health Presbyterian Hospital, Dallas, TX; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, and Division of Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA; Infectious Diseases Institute, Mulago Hospital Complex, Kampala, Uganda; Division of Infectious Diseases, Department of Internal Medicine, Texas Health Presbyterian Hospital, Dallas, TX; Division of Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA; Department of Internal Medicine, Renal Section, Texas Health Presbyterian Hospital, Dallas, TX; Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE; Department of Internal Medicine, Texas Health Presbyterian Hospital, Dallas, TX; Division of Critical Care, Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA.

Critical Care Medicine

|May 17, 2016

Summary

No abstract available in PubMed .

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