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Updated: Mar 21, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
Identification of a novel HLA-A allele, HLA-A*01:195, in a UAE national
Wael Abdrabou1, Ini-Isabée Witzel1, Agnieszka Paduch2
1Department of Biomedical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Abstract:
A novel human leucocyte antigen (HLA)-A allele, HLA-A*01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A*01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the α2 domain of the α chain of the mature protein). This A to G mutation results in an amino acid change of isoleucine #124 to valine.

