[Treatment of migraine with vasopressin]

Clinicophysiological studies were performed in 186 patients with different variants of migraine. Of these, 153 received a course of treatment with the neuropeptide 8-arginine vasopressin. The pain paroxysms were reduced in intensity and duration in 87% of the cases in which also the cerebral hemodynamics, psychoemotional state, autonomic vascular conditions and working capacities improved. Prophylactic courses yielded positive results in 63 patients. The therapeutic effectiveness of 8-arginine vasopressin, and the simplicity of its administration without untoward effects and complications allowed us to recommend the drug to use in migraines, especially during the attacks.