Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic nerve sectioning does not affect the development of the retina.

D T Yew1, D R Zhang, B S Hui

  • 1Department of Anatomy, Chinese University of Hong Kong, Shatin NT.

Acta Anatomica
|January 1, 1989
PubMed
Summary

Optic nerve sectioning in albino rats on postnatal day 2 did not impede retinal development. Minor variations in outer segment size were observed, but overall retinal growth remained unaffected.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Brain functional and cognitive features in schizophrenia patients with positive and negative symptom features based on resting-state functional MRI].

Zhonghua yi xue za zhi·2026
Same author

[Treatment practice and outcomes in 125 patients with autoimmune hemolytic anemia: a single-center retrospective analysis].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2026
Same author

[Prefrontal near-infrared spectroscopy characteristics in patients with schizophrenia during verbal fluency tasks and their association with clinical efficacy].

Zhonghua yi xue za zhi·2026
Same author

[A randomized controlled trial of knotless barbed sutures for wound closure in short-segment posterior lumbar decompression and fusion surgery].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2026
Same author

[Incidence and associated factors of tyrosine kinase inhibitor withdrawal syndrome and psychological issues in patients with chronic-phase chronic myeloid leukemia after therapy discontinuation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[Clinical prognostic prediction research: a technical roadmap].

Zhonghua yi xue za zhi·2025

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Ophthalmology

Background:

  • The developing retina relies on visual input for maturation.
  • Optic nerve development is crucial for retinal cell differentiation and survival.

Purpose of the Study:

  • To investigate the impact of early optic nerve sectioning on albino rat retinal development.
  • To determine if visual pathway interruption affects retinal growth and differentiation at a critical early stage.

Main Methods:

  • Albino rats underwent optic nerve transection on the second postnatal day.
  • Retinal development was monitored and compared between experimental and control groups.
  • Histological analysis was performed to assess cellular layers and structures.

Related Experiment Videos

Main Results:

  • Optic nerve sectioning at postnatal day 2 did not significantly alter overall retinal development.
  • Both experimental and control retinas exhibited similar developmental trajectories.
  • Slight, non-significant retardations were noted in the size of outer segments in experimental retinas.

Conclusions:

  • Early interruption of the optic nerve in albino rats does not prevent normal retinal development.
  • The retina at this developmental stage appears capable of progressing without intact visual input.
  • Further research may explore the long-term effects or specific cellular responses to optic nerve injury.