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Updated: Mar 21, 2026

Extraction and Analysis of Taiwanese Green Propolis
Published on: January 7, 2019
Brazilian Green Propolis Improves Antioxidant Function in Patients with Type 2 Diabetes Mellitus
Liting Zhao1,2, Lingling Pu3, Jingyu Wei4
1Department of Nutrition, Tianjin Institute of Health and Environmental Medicine, Tianjin 300050, China. zlt_medic@126.com.
Abstract:
Propolis contains a variety of bioactive components and possesses many biological properties. This study was designed to evaluate potential effects of Brazilian green propolis on glucose metabolism and antioxidant function in patients with type 2 diabetes mellitus (T2DM). In the 18-week randomized controlled study, enrolled patients with T2DM were randomly assigned to Brazilian green propolis group (900 mg/day) (n = 32) and control group (n = 33). At the end of the study, no significant difference was found in serum glucose, glycosylated hemoglobin, insulin, aldose reductase or adiponectin between the two groups. However, serum GSH and total polyphenols were significantly increased, and serum carbonyls and lactate dehydrogenase activity were significantly reduced in the Brazilian green propolis group. Serum TNF-α was significantly decreased, whereas serum IL-1β and IL-6 were significantly increased in the Brazilian green propolis group. It is concluded that Brazilian green propolis is effective in improving antioxidant function in T2DM patients.
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