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Effects of TiF4 solutions on root surfaces in vitro after different application periods
L Skartveit1, A B Tveit, B Tøtdal
1Department of Dental Research, School of Dentistry, University of Bergen, Norway.
Acta Odontologica Scandinavica
|February 1, 1989
Summary
Titanium tetrafluoride (TiF4) effectively delivers fluoride to tooth root surfaces. Application time and TiF4 concentration can be reduced while maintaining high fluoride uptake, indicating clinical efficacy.
Area of Science:
- Biomaterials Science
- Dental Research
- Fluoride Chemistry
Background:
- Topical fluoride application is crucial for preventing dental caries.
- Titanium tetrafluoride (TiF4) demonstrates rapid fluoride uptake on root surfaces.
Purpose of the Study:
- To determine if reduced application periods and/or lower ionic strength of TiF4 solutions affect fluoride uptake.
- To assess the optimal conditions for TiF4 application on human tooth root surfaces.
Main Methods:
- Human tooth root halves were treated with varying concentrations (1% and 3.4%) and application times (10 sec to 4 min) of TiF4.
- Control surfaces were protected with nail polish.
- Fluoride and titanium concentrations were analyzed using electron microprobe analysis on ground sections.
Main Results:
- Treated root surfaces showed significantly higher fluoride concentrations (0.60-1.94%) compared to controls (<0.30%).
- Similar fluoride concentrations were achieved with both 1% and 3.4% TiF4 solutions.
- Reduced application time led to shallower fluoride penetration but minimal reduction in surface fluoride concentration.
- High titanium concentrations were detected on all treated surfaces.
Conclusions:
- Both application period and ionic strength of TiF4 solutions can be substantially reduced without compromising high fluoride uptake.
- TiF4 is a potentially effective agent for clinical topical fluoride application on root surfaces.