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Infant-feeding practices and American Indian infants' gut microbiome: Rationale of the pilot study

Anna Zamora-Kapoor, Ka'imi Sinclair

    Breastfeeding Review : Professional Publication of the Nursing Mothers' Association of Australia
    |May 19, 2016
    PubMed

    Insights

    This study explores infant feeding practices and the gut microbiome in American Indian infants to understand childhood obesity causes. Findings will inform future research and prevention strategies for this population.

    Area of Science:

    • Microbiome research
    • Pediatric obesity
    • Nutritional science

    Background:

    • High prevalence of obesity in American Indian infants.
    • Underlying causes of infant obesity in this population remain unclear.
    • Need to investigate factors like infant feeding practices.

    Purpose of the Study:

    • Examine the relationship between infant feeding practices and the gut microbiome in American Indian infants.
    • Lay the foundation for a research program on childhood obesity aetiologies.
    • Identify potential prevention strategies for childhood obesity.

    Main Methods:

    • Combines qualitative and quantitative data.
    • Utilizes DNA sequencing for gut microbiome analysis.
    • Examines maternal attitudes, dietary habits, and physical activity.

    Main Results:

    • The study protocol is described, including theoretical basis, target population rationale, study design, recruitment, and data analysis.
    • Aims to generate data on gut microbiome yield, quality, and diversity.
    • Results will inform a larger proposed study.

    Conclusions:

    • The study protocol provides a framework for investigating infant feeding, gut microbiome, and obesity.
    • Results will guide future research into obesity aetiologies in American Indian infants.
    • Aims to identify effective prevention strategies for childhood obesity.

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