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Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the
Kathy Laber1, Christian E Newcomer2, Thierry Decelle3
1Chief, Comparative Medicine Branch, NIEHS/NIH, Research Triangle Park, NC, USA kathy.laber@nih.gov.
Abstract:
International regulations and guidelines strongly suggest that the use of animal models in scientific research should be initiated only after the authority responsible for the review of animal studies has concluded a well-thought-out harm-benefit analysis (HBA) and deemed the project to be appropriate. The AALAS-FELASA working group on HBA has performed a literature review and based on this review, proposed a method for HBA. Examples of the working group's approach are included in this report.
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