Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

10.7K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
10.7K
Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

7.2K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
7.2K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dome-shaped macula in high myopia: Prevalence and clinical characteristics in a French cohort.

Acta ophthalmologica·2026
Same author

Current practice patterns for cleaning tonometry tips and diagnostic/laser lenses.

Journal of cataract and refractive surgery·2026
Same author

Genome-wide discovery reveals 30 loci for choroidal thickness and uncovers potential causal links with angle-closure glaucoma.

medRxiv : the preprint server for health sciences·2026
Same author

Telomerase is induced during wound healing across species.

Skin health and disease·2026
Same author

Clinical Outcomes of a New Topical Corticosteroid with Greater Theoretical Potency.

Ophthalmology·2026
Same author

Bag-in-the-lens technique.

Frontiers in ophthalmology·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Buruli ulcer in Africa: between innovation and pragmatism.

Nature reviews. Disease primers·2026
Same journal

Author Correction: Atopic dermatitis.

Nature reviews. Disease primers·2026
See all related articles

Related Experiment Video

Updated: Mar 21, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
05:19

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Published on: December 1, 2023

1.8K

Cataract.

Dennis Lam1,2, Srinivas K Rao3, Vineet Ratra2

  • 1State Key Laboratory of Ophthalmology, and Zhongshan Ophthalmic Center, Sun Yat-Sen University, 54 South Xianlie Road, Guangzhou 510060, China.

Nature Reviews. Disease Primers
|May 19, 2016
PubMed
Summary
This summary is machine-generated.

Cataract surgery is the only treatment for reversible blindness, with phacoemulsification being standard in developed nations. Improving surgical access in developing countries is crucial due to a growing backlog of patients.

More Related Videos

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
13:56

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

10.4K
Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
04:59

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

Published on: July 7, 2023

3.2K

Related Experiment Videos

Last Updated: Mar 21, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
05:19

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery

Published on: December 1, 2023

1.8K
Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
13:56

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

10.4K
Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
04:59

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

Published on: July 7, 2023

3.2K

Area of Science:

  • Ophthalmology
  • Global Health
  • Surgical Innovation

Background:

  • Cataract is the primary cause of reversible blindness and visual impairment worldwide.
  • Blindness due to cataracts disproportionately affects low socioeconomic populations in developing countries.
  • Cataract surgery remains the sole effective treatment for vision restoration.

Purpose of the Study:

  • To review current cataract treatment modalities and their global disparities.
  • To highlight challenges in delivering cataract surgical services, particularly in underserved regions.
  • To emphasize the need for efficient service delivery models to address the backlog of cataract blindness.

Main Methods:

  • Review of established cataract surgery techniques: phacoemulsification (developed world standard) and manual small incision cataract surgery (developing country frequent use).
  • Evaluation of emerging technologies like femtosecond laser-assisted cataract surgery, noting pending clinical trial data.
  • Analysis of factors contributing to the growing backlog of cataract blindness, including access to affordable surgery and surgeon training limitations.

Main Results:

  • Surgical outcomes for cataracts are generally positive, with effective management of complications like endophthalmitis.
  • Current data do not indicate superiority of femtosecond laser-assisted cataract surgery over existing methods.
  • Significant challenges persist in providing timely and affordable cataract surgery to underserved populations, exacerbated by aging demographics.

Conclusions:

  • Effective management of cataract blindness requires focusing resources on efficient surgical service delivery models in underserved areas.
  • Addressing the global backlog necessitates innovative approaches beyond simply increasing surgeon numbers.
  • While surgical techniques evolve, equitable access to care remains the paramount challenge in combating cataract-induced vision impairment.