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Related Concept Videos

Skin Cancer01:30

Skin Cancer

6.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.6K

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Related Experiment Video

Updated: Mar 21, 2026

Establishment of a Clinic-based Biorepository
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Establishment of a Clinic-based Biorepository

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[Basal cell carcinoma surgery].

Martin Glud1, Silje Haukali Omland, Robert Gniadecki

  • 1glud.martin@gmail.com.

Ugeskrift for Laeger
|May 19, 2016
PubMed
Summary

Basal cell carcinoma (BCC), the most common human cancer, requires complete tumor eradication. Treatment choice for BCC depends on risk factors like tumor aggressiveness and location, aiming for functional and cosmetic preservation.

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Oncology

Background:

  • Basal cell carcinoma (BCC) is the most prevalent human cancer, with a 30% lifetime risk.
  • Effective BCC treatment necessitates complete tumor eradication while preserving function and cosmetic outcomes.
  • Recurrence risk is elevated for aggressive, facial H-zone, or previously treated BCCs.

Purpose of the Study:

  • To outline the treatment scope for basal cell carcinoma.
  • To identify risk factors associated with BCC recurrence.
  • To differentiate treatment strategies for high-risk versus low-risk BCC.

Main Methods:

  • Review of current treatment modalities for basal cell carcinoma.
  • Analysis of factors influencing BCC recurrence.

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  • Categorization of BCC into high-risk and low-risk groups.
  • Main Results:

    • High-risk BCCs are optimally treated with surgical excision or radiotherapy.
    • Low-risk BCCs can be managed with cryotherapy, curettage, photodynamic therapy, or topical agents.
    • Tumor aggressiveness, facial H-zone location, and prior treatment influence recurrence risk.

    Conclusions:

    • Treatment selection for BCC should be risk-stratified.
    • Surgical excision and radiotherapy are primary options for high-risk BCC.
    • Less invasive methods are suitable for low-risk BCC, balancing efficacy with patient outcomes.