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High-Throughput Analysis of Optical Mapping Data Using ElectroMap
Published on: June 4, 2019
Full Monte Carlo and measurement-based overall performance assessment of improved clinical implementation of eMC
Jarkko Ojala1, Mika Kapanen1, Simo Hyödynmaa2
1Department of Oncology, Unit of Radiotherapy, Tampere University Hospital, P.O. Box 2000, FI-33521 Tampere, Finland; Department of Medical Physics, Medical Imaging Center, Tampere University Hospital, P.O. Box 2000, FI-33521 Tampere, Finland.
Abstract:
New version 13.6.23 of the electron Monte Carlo (eMC) algorithm in Varian Eclipse™ treatment planning system has a model for 4MeV electron beam and some general improvements for dose calculation. This study provides the first overall accuracy assessment of this algorithm against full Monte Carlo (MC) simulations for electron beams from 4MeV to 16MeV with most emphasis on the lower energy range. Beams in a homogeneous water phantom and clinical treatment plans were investigated including measurements in the water phantom. Two different material sets were used with full MC: (1) the one applied in the eMC algorithm and (2) the one included in the Eclipse™ for other algorithms. The results of clinical treatment plans were also compared to those of the older eMC version 11.0.31. In the water phantom the dose differences against the full MC were mostly less than 3% with distance-to-agreement (DTA) values within 2mm. Larger discrepancies were obtained in build-up regions, at depths near the maximum electron ranges and with small apertures. For the clinical treatment plans the overall dose differences were mostly within 3% or 2mm with the first material set. Larger differences were observed for a large 4MeV beam entering curved patient surface with extended SSD and also in regions of large dose gradients. Still the DTA values were within 3mm. The discrepancies between the eMC and the full MC were generally larger for the second material set. The version 11.0.31 performed always inferiorly, when compared to the 13.6.23.
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