Ketoconazole-induced estrogen deficiency causes transient decrease in placental blood flow associated with hypoxia

Aoi Ichikawa1, Hiromichi Tamada2

  • 1Drug Safety Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa 251-8555, Japan; Department of Advanced Pathobiology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka 598-8531, Japan.