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Updated: Mar 21, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
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Protecting bone in long-term HIV positive patients receiving antiretrovirals

Tara McGinty1, Patrick Mallon1

  • 1a School of Medicine , University College Dublin , Dublin , Ireland.

Expert Review of Anti-Infective Therapy
|May 19, 2016
PubMed

Insights

Maintaining bone health is crucial for aging individuals with HIV, as they face higher risks of low bone mineral density (BMD) and fractures. This review covers strategies for screening and managing bone health in this population.

Area of Science:

  • Bone health in aging populations
  • HIV medicine
  • Gerontology

Background:

  • Aging individuals with HIV experience increased non-AIDS morbidities.
  • Low bone mineral density (BMD) and fractures are more prevalent in the HIV-positive population.
  • Fragility fractures are a significant cause of morbidity and mortality in people with HIV.

Purpose of the Study:

  • To review strategies for maintaining bone health in people living with HIV.
  • To discuss screening and management of low BMD and fractures.
  • To explore the role of antiretroviral therapy in bone health.

Main Methods:

  • Literature review of current strategies.
  • Analysis of the impact of antiretroviral therapy on bone health.
  • Discussion of expert commentary and future perspectives.

Main Results:

  • Increased fracture rates and low BMD are observed in people with HIV.
  • Antiretroviral therapy choice and modification can impact bone health.
  • Comprehensive management strategies are needed for bone health in aging HIV patients.

Conclusions:

  • Proactive management of bone health is essential for people aging with HIV.
  • Screening and intervention for low BMD and fracture prevention are critical.
  • Further research into optimizing bone health in the context of HIV and aging is warranted.
Abstract

Keywords:
BoneHIVantiretroviral therapybisphosphonatesbone mineral densityfractures in HIVosteoporosis

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