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Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
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Differential distribution improves gene selection stability and has competitive classification performance for

Dario Strbenac1, Graham J Mann2, Jean Y H Yang1

  • 1School of Mathematics and Statistics, University of Sydney, NSW 2006, Australia.

Nucleic Acids Research
|May 19, 2016
PubMed
Summary

This study introduces differential distribution (DD) to identify gene biomarkers by combining differential expression (DE) and differential variability (DV). DD improves gene selection stability and uncovers complementary biomarkers for better cancer prediction and treatment.

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