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Chronic Anterior Uveitis in Children
Cristóbal Couto1, Mercedes M Frick1, Kara LaMattina2
1a Uveitis Clinics, Department of Ophthalmology , University of Buenos Aires , Buenos Aires , Argentina.
Insights
Visual prognosis for pediatric chronic anterior uveitis is good, though remission is uncommon. Long-term follow-up is often needed for juvenile idiopathic arthritis patients to achieve remission.
Area of Science:
- Ophthalmology
- Pediatrics
- Rheumatology
Background:
- Chronic anterior uveitis in children often presents with juvenile idiopathic arthritis (JIA).
- Understanding visual prognosis and remission rates is crucial for managing this condition.
- JIA is a common underlying cause of chronic anterior uveitis in pediatric populations.
Purpose of the Study:
- To determine the visual prognosis of chronic anterior uveitis in pediatric patients.
- To evaluate the remission rate of chronic anterior uveitis in children.
- To identify factors influencing visual outcomes and remission in pediatric uveitis.
Main Methods:
- Retrospective case series of pediatric patients with chronic anterior uveitis.
- Diagnosis of JIA based on International League of Associations for Rheumatology criteria.
- Uveitis remission defined using SUN criteria.
Main Results:
- 35 pediatric patients (61 eyes) were included, with a mean age of onset at 7.69 years.
- 60% of patients were female, and 74% had bilateral disease; oligoarthritis was the most common JIA form.
- Higher remission rates were observed in males (p=0.031), with a median follow-up of 60 months.
Conclusions:
- Visual prognosis for pediatric chronic anterior uveitis is generally good.
- Remission is not common and typically requires long-term follow-up.
- Early diagnosis and management are essential for favorable visual outcomes.
Purpose:
To describe the visual prognosis and remission rate of chronic anterior uveitis in pediatric patients.
Methods:
A retrospective case series of children with chronic anterior uveitis treated in the University of Buenos Aires. Juvenile idiopathic arthritis was defined according to the International League of Associations for Rheumatology criteria. Uveitis remission was defined according to SUN criteria.
Results:
There were 35 pediatric patients (61 eyes), mean age of uveitis onset was 7.69 ± 3 years, 60% were females and 74% had bilateral disease, median follow-up was 60 months (range: 12-192 months). JIA was more frequent in females (80.95 vs 21.43; p<0.0001) and oligoarthritis was the most common form. Remission rate was higher in males (HR = 4.99; 95% CI = 1.16-21.51; p = 0.031). More than 40 eyes remained with the same BCVA at 1 year of follow-up.
Conclusions:
Although remission was not common and only occurred after long-term follow-up, visual prognosis was good Received 30 August 2015; revised 6 March 2016; accepted 14 March 2016; published online 18 May 2016.
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