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Effects of Well-Controlled HIV Infection on Complement Activation and Function.

Alexandria E-B Rossheim1, Tina D Cunningham, Pamela S Hair

  • 1*Division of Infectious Diseases, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA; †Center for Health Analytics and Discovery, Office of Research, Eastern Virginia Medical School, Norfolk, VA; ‡Department of Pediatrics, Eastern Virginia Medical School, Norfolk, VA; §Children's Specialty Group, Norfolk, VA; and ‖Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA.

Journal of Acquired Immune Deficiency Syndromes (1999)
|May 19, 2016
PubMed
Summary

Even with controlled HIV infection, complement activation persists, contributing to chronic inflammation. Hepatitis C coinfection further elevates this inflammatory response, indicating a heightened proinflammatory state.

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