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Related Experiment Video

Updated: Mar 21, 2026

Anterior Capsular Reconstruction with Human Dermal Allograft for Irreparable Subscapularis Tears
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Scleroderma en coup de sabre treated with polymethylmethacrylate - Case report.

Joanna Pimenta de Araujo Franco1, Márcio Soares Serra1, Ricardo Barbosa Lima1

  • 1Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Anais Brasileiros De Dermatologia
|May 19, 2016
PubMed
Summary

Scleroderma en coup de sabre, a childhood skin condition, causes facial deformities. Polymethylmethacrylate (PMMA) offers a safe and effective alternative filler for treating these deformities, yielding excellent aesthetic outcomes.

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Area of Science:

  • Dermatology
  • Plastic Surgery

Background:

  • Scleroderma en coup de sabre is a localized scleroderma variant primarily affecting children.
  • Treatment involves surgical techniques like fillers, fat grafting, and lesion resection to address atrophy and deformity.
  • Hyaluronic acid is a common filler, but limitations necessitate exploring alternatives.

Observation:

  • Polymethylmethacrylate (PMMA) is a permanent, biocompatible, non-toxic, non-mutagenic, and immunologically inert filler.
  • A case report details the successful treatment of a 17-year-old with scleroderma en coup de sabre using PMMA.

Findings:

  • Polymethylmethacrylate (PMMA) demonstrated excellent aesthetic results in treating scleroderma en coup de sabre.
  • The study highlights PMMA as a viable alternative filler for managing this condition.

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Last Updated: Mar 21, 2026

Anterior Capsular Reconstruction with Human Dermal Allograft for Irreparable Subscapularis Tears
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Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
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Implications:

  • Polymethylmethacrylate (PMMA) presents a promising alternative for reconstructive surgery in localized scleroderma.
  • Further research into PMMA's long-term efficacy and safety in pediatric dermatology is warranted.