Related Experiment Video
Updated: Mar 21, 2026

07:00
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
6.4K
[One case report of nasal sinus ossification]
Summary
A pediatric osteofibroma caused left eye proptosis. Surgical resection of the ethmoid, maxillary, and sphenoid sinuses successfully treated the condition with no recurrence.
Area of Science:
- Otolaryngology and Orbital Surgery
- Pediatric Oncology
- Medical Imaging
Background:
- Osteofibromas are rare benign bone tumors that can affect craniofacial structures.
- Orbital and sinonasal osteofibromas in pediatric patients present unique diagnostic and surgical challenges.
- Early diagnosis and intervention are crucial to prevent complications such as proptosis and vision impairment.
Observation:
- An 8-year-old male presented with a one-month history of left eye proptosis (bulging).
- Physical examination revealed lateral nasal wall movement and a narrowed left nasal cavity.
- Orbital CT imaging demonstrated extensive damage to the left ethmoid sinus, maxillary sinus, sphenoid sinus, and nasal cavity.
Findings:
- A complex osteofibroma involving multiple sinonasal and orbital structures was diagnosed.
- Surgical resection was performed using a combined approach targeting the left maxillary, ethmoid, and sphenoid sinuses.
- Histopathological examination confirmed the diagnosis of osteofibroma.
Implications:
- Combined surgical approaches can effectively resect extensive sinonasal and orbital osteofibromas in children.
- This case highlights the importance of multidisciplinary collaboration in managing rare pediatric tumors.
- Successful surgical management led to satisfactory recovery and a long-term absence of recurrence, preserving ocular and sinonasal function.
Related Concept Videos
Cranial Bones: Lateral View
7.8K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
7.8K
Nose and Nasal Cavity
14.9K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
14.9K
Anatomy of Respiratory System I: Upper Respiratory Tract
6.3K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
6.3K
Sutures of the Skull
14.1K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
14.1K
Epistaxis
703
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
703
Physical Assessment of the Respiratory Tract I: Health History
1.2K
Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
1.2K

