Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

728
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
728
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

605
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
605
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

1.2K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.2K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.3K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.3K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

531
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
531
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

5.0K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radical Resection Using the Commando Procedure for Recurrent Cardiac Intimal Sarcoma in a Young Adult: A Case Report.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·2026
Same author

Stent-Assisted Double Microcatheter Coil Embolization for an Inferior Pancreaticoduodenal Artery Aneurysm after Multiple Stent-Graft Procedures: A Case Report.

Annals of vascular diseases·2026
Same author

Endovascular Management of Moyamoya Type II Endoleak Utilizing a CO<sub>2</sub>-Assisted Protection Strategy: A Case Report.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists·2026
Same author

Hybrid Approach for Multiple Visceral Aneurysms with Isolated Dissection at the Superior Mesenteric Artery: A Case Report.

Annals of vascular diseases·2025
Same author

Patient Outcomes after Introduction of Novel Myocardial Protection Protocol for Prolonged Aortic Cross-Clamping.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·2025
Same author

XOR-Derived ROS in Tie2-Lineage Cells Including Endothelial Cells Promotes Aortic Aneurysm Progression in Marfan Syndrome.

Arteriosclerosis, thrombosis, and vascular biology·2025

Related Experiment Video

Updated: Mar 21, 2026

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
07:41

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats

Published on: March 1, 2022

3.5K

Reversible decline in pulmonary function during left ventricular assist device therapy.

Teruhiko Imamura1, Koichiro Kinugawa2, Osamu Kinoshita3

  • 1Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. te.imamu@gmail.com.

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs
|May 20, 2016
PubMed
Summary

Cardiac replacement therapy using a left ventricular assist device (LVAD) can temporarily decrease pulmonary function. However, lung function often recovers after a heart transplant, especially with shorter LVAD support durations.

Keywords:
Heart failureHeart transplantationTidal volume

More Related Videos

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.5K
Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
05:18

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure

Published on: January 16, 2026

133

Related Experiment Videos

Last Updated: Mar 21, 2026

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
07:41

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats

Published on: March 1, 2022

3.5K
Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.5K
Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
05:18

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure

Published on: January 16, 2026

133

Area of Science:

  • Cardiology
  • Pulmonology
  • Medical Engineering

Background:

  • Cardiac replacement therapy, including LVAD and heart transplantation, improves outcomes for end-stage heart failure.
  • The effects of LVAD therapy on pulmonary function are not well understood.

Purpose of the Study:

  • To investigate the impact of LVAD support and subsequent heart transplantation on pulmonary function.
  • To determine if pulmonary function changes are reversible after heart transplantation.

Main Methods:

  • Retrospective analysis of pulmonary function tests in 22 patients with stage D heart failure.
  • Data collected during pre-heart failure, LVAD support, and post-heart transplantation periods.
  • Statistical analysis to assess changes in % vital capacity and FEV1.

Main Results:

  • Pulmonary function, specifically % vital capacity and FEV1, significantly decreased after LVAD implantation.
  • % vital capacity and FEV1 returned to baseline levels following heart transplantation.
  • Shorter LVAD support duration correlated with greater improvement in % vital capacity post-transplant.

Conclusions:

  • LVAD support is associated with a reversible decline in pulmonary function.
  • Pulmonary dysfunction during LVAD support may be mitigated by limiting the duration of device support.
  • Heart transplantation can restore pulmonary function impaired by LVAD therapy.