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Plasticity

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Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...

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Related Experiment Video

Updated: Mar 21, 2026

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

Inhibitory interneurons in visual cortical plasticity.

Daniëlle van Versendaal¹, Christiaan N Levelt^2,3

¹Department of Molecular Visual Plasticity, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.

Cellular and Molecular Life Sciences : CMLS

|May 20, 2016

Summary

This summary is machine-generated.

Sensory stimuli are vital for neocortical development during critical periods. Specific interneuron subsets regulate plasticity, guiding which neuronal inputs mature in the developing brain.

Keywords:

Adult Inhibition V1 Neurogliaform cells Ocular dominance plasticity Parvalbumin Perceptual learning Somatostatin Vasoactive intestinal peptide

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Related Experiment Videos

Last Updated: Mar 21, 2026

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

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Published on: February 8, 2020

A Guide to In vivo Single-unit Recording from Optogenetically Identified Cortical Inhibitory Interneurons

A Guide to In vivo Single-unit Recording from Optogenetically Identified Cortical Inhibitory Interneurons

Published on: November 7, 2014

Area of Science:

Neuroscience
Developmental Biology
Cortical Plasticity

Background:

Neocortical maturation requires sensory exposure during critical developmental periods.
Ending these periods is crucial for stable cortical processing and shifts to conditional learning.
Inhibitory innervation is key to regulating plasticity in the primary visual cortex.

Purpose of the Study:

To discuss how distinct interneuron subsets regulate plasticity across different stages of cortical maturation.
To propose a theoretical framework for interneuron-mediated selection of plastic neuronal inputs.

Main Methods:

Review of existing literature on cortical plasticity and interneuron function.
Analysis of age-dependent plasticity mechanisms in the primary visual cortex.
Theoretical modeling of interneuron roles in synaptic refinement.

Main Results:

Inhibitory innervation dynamics are critical for plasticity.
A transient decrease in inhibition facilitates plasticity.
Different interneuron populations modulate plasticity at distinct developmental stages.

Conclusions:

Interneuron subsets play differential roles in regulating cortical plasticity.
These subsets selectively guide the plasticity of specific neuronal input sources.
This mechanism contributes to the precise maturation of cortical functions and skills.