Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.1K
The Skin Microbiota01:27

The Skin Microbiota

16
The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
16
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

16
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
16
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

681
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
681
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

2.0K
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
2.0K
Papillary Dermis01:11

Papillary Dermis

6.6K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishment of epidemiological cutoff values against <i>Fonsecaea monophora</i>, an agent of chromoblastomycosis and cerebral phaeohyphomycosis.

Journal of clinical microbiology·2026
Same author

Psychosocial impact of unemployment: Validation of the PSIUS and spatial distribution of latent classes in an urban Chilean community.

Acta psychologica·2026
Same author

Reply to Chen et al., "Methodological considerations for the establishment of epidemiological cutoff values for <i>Sporothrix</i> species using CLSI broth microdilution".

Antimicrobial agents and chemotherapy·2026
Same author

Sporotrichosis in patients with diabetes mellitus: A systematic review of individual participant data.

Medical mycology·2026
Same author

Cryptococcosis mimicking lung cancer in an immunocompetent patient: A case report.

Indian journal of medical microbiology·2026
Same author

Pulmonary mucormycosis with endobronchial involvement due to <i>Rhizopus homothallicus</i>: a fatal case report.

Medical mycology case reports·2026

Related Experiment Video

Updated: Mar 21, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

11.3K

Superficial Mycoses Associated with Diaper Dermatitis.

Alexandro Bonifaz1, Rubí Rojas2, Andrés Tirado-Sánchez3

  • 1Department of Mycology and Dermatology Service, Hospital General de México, "Dr. Eduardo Liceaga", Dr. Balmis 148, Col Doctores, CP 06720, Mexico, DF, Mexico. a_bonifaz@yahoo.com.mx.

Mycopathologia
|May 20, 2016
PubMed
Summary

Diaper area infections are often caused by Candida yeasts, necessitating accurate diagnosis for effective topical antifungal treatment. Other fungi like dermatophytes and Malassezia, plus conditions like erythrasma, also require specific management strategies.

Keywords:
Candida albicansDermatophytosisDiaper dermatitisEpidermophyton floccosumMalassezia spp.

More Related Videos

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
03:24

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging

Published on: March 22, 2024

2.3K
Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

14.8K

Related Experiment Videos

Last Updated: Mar 21, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

11.3K
Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
03:24

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging

Published on: March 22, 2024

2.3K
Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

14.8K

Area of Science:

  • Dermatology
  • Mycology
  • Infectious Diseases

Background:

  • Diaper environments promote fungal growth due to moisture, friction, and altered pH.
  • Candida yeasts, particularly Candida albicans, are the most common cause of secondary infections in the diaper area, found in over 80% of cases.
  • Other fungi like dermatophytes and Malassezia, as well as the bacterial pseudomycosis erythrasma, can also affect this region.

Purpose of the Study:

  • To review the common fungal and pseudomycosis infections in the diaper area.
  • To highlight the importance of accurate diagnosis for appropriate treatment selection.
  • To discuss the specific characteristics and management of candidiasis, dermatophytosis, Malassezia-related conditions, and erythrasma.

Main Methods:

  • Literature review of fungal and pseudomycosis infections in diaper areas.
  • Analysis of etiological agents, clinical presentations, and treatment options.
  • Emphasis on differential diagnosis between various conditions.

Main Results:

  • Candida albicans is the predominant pathogen (>80%), requiring specific topical antimycotics like nystatin, imidazoles, or ciclopirox, with awareness of resistant strains.
  • Dermatophytosis, caused by agents like Epidermophyton floccosum, presents differently and is easily diagnosed and treated.
  • Malassezia yeasts can exacerbate existing skin conditions, and erythrasma is a bacterial pseudomycosis mimicking candidiasis.

Conclusions:

  • Accurate diagnosis is crucial for effective treatment of diaper area infections.
  • Topical antimycotics are effective for candidiasis, but resistance should be considered.
  • Dermatophytosis, Malassezia exacerbations, and erythrasma require distinct diagnostic and therapeutic approaches.