Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 21, 2026

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

10.2K

Inverse correlation between longevity and developmental rate among wild C. elegans strains.

Yujin Lee1, Wooseon Hwang1, Juyoung Jung1

  • 1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea.

Aging
|May 20, 2016
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimation of comparable standardized mean differences in cluster randomized trials with covariate adjustment.

The British journal of mathematical and statistical psychology·2026
Same author

Gut microbe-generated metabolite trimethylamine N-oxide and risk of abdominal aortic aneurysm: a cohort study.

European heart journal·2026
Same author

Primary Healthcare Utilization of Undocumented Migrants in Busan, South Korea: A Retrospective Chart Review of a Free Clinic From 2020 to 2024.

Journal of preventive medicine and public health = Yebang Uihakhoe chi·2026
Same author

Clinical Outcomes of Non-Operative Versus Operative Treatment in Adhesive Small Bowel Obstruction: A Systematic Review and Meta-Analysis.

ANZ journal of surgery·2026
Same author

Submicron interfacial layers for nanoscale control of lithium deposition in surface-engineered current collectors.

Nanoscale·2026
Same author

Factors Associated With Preoperative Radiological Tumor Size Underestimation in Clinical T1-2 Breast Cancer Patients.

The breast journal·2026

Wild C. elegans strains show that longevity and fitness are not always linked. Genetic variations influence how resources are allocated to lifespan and development in these worms.

Area of Science:

  • Evolutionary Biology
  • Genetics
  • Gerontology

Background:

  • Long-lived mutants in model organisms often exhibit reduced fitness.
  • In wild animals, the link between longevity and fitness is less clear, suggesting complex genetic factors.
  • The relationship between lifespan and fitness in natural populations requires further investigation.

Purpose of the Study:

  • To investigate the correlation between lifespan, fitness, developmental rate, and brood size in wild-derived C. elegans strains.
  • To explore the role of genetic variation in resource allocation between longevity and development in natural isolates.

Main Methods:

  • Utilized 16 wild-derived Caenorhabditis elegans (C. elegans) strains from diverse geographic origins.
  • Quantified lifespan, developmental rate, and brood size (a measure of fitness) for each strain.
Keywords:
C. elegansagingdevelopmentfitnesslifespanreproduction

More Related Videos

Measuring Caenorhabditis elegans Life Span on Solid Media
12:49

Measuring Caenorhabditis elegans Life Span on Solid Media

Published on: May 12, 2009

31.2K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

4.3K

Related Experiment Videos

Last Updated: Mar 21, 2026

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
11:58

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan

Published on: June 29, 2018

10.2K
Measuring Caenorhabditis elegans Life Span on Solid Media
12:49

Measuring Caenorhabditis elegans Life Span on Solid Media

Published on: May 12, 2009

31.2K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

4.3K
  • Analyzed correlations between these traits across different strains.

    • Main Results:

    • A negative correlation was observed between lifespan and developmental rate across C. elegans strains.
    • However, this negative correlation was not found between longevity and developmental rate within individual C. elegans strains.
    • These findings suggest strain-specific genetic influences on trait allocation.

    Conclusions:

    • Polymorphic genetic variants in wild C. elegans isolates play a crucial role in determining resource allocation strategies.
    • These genetic differences influence the trade-offs between longevity and developmental rate.
    • The study highlights the complexity of the longevity-fitness relationship in natural populations.