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"Reverse Tigroid" Pattern in Pachygyria: A Novel Finding.

Ujjawal Roy¹, Alak Pandit¹, Urmila Das¹

¹Department of Neurology, Bangur Institute of Neurosciences, IPGMER, Kolkata, West Bengal, India.

Journal of Clinical Imaging Science

|May 20, 2016

Summary

This summary is machine-generated.

Pachygyria, a brain development disorder, can show unusual MRI patterns. This case highlights atypical "tigroid" and "leopard" patterns on brain MRI in pachygyria, previously unreported.

Keywords:

Lissencephaly malformations of cortical development metachromatic leukodystrophy

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Area of Science:

Neurology
Radiology
Developmental Neuroscience

Background:

Pachygyria is a subtype of lissencephaly, characterized by abnormal neuronal migration.
Clinical manifestations include microcephaly, developmental delay, seizures, and cognitive impairment.
Brain MRI is crucial for diagnosis and management planning.

Observation:

A case of pachygyria presented with atypical neuroimaging findings.
The brain MRI revealed "tigroid-like stripes" on axial views and a "leopard-like pattern" on sagittal views.
These specific MRI patterns have not been previously documented in pachygyria.

Findings:

The observed MRI patterns mimicked those typically seen in myelin formation disorders.
This presentation challenges the classical interpretation of these specific MRI findings.
The case underscores the variability of neuroimaging in neuronal migration disorders.

Implications:

Broadens the spectrum of MRI findings associated with pachygyria.
May prompt re-evaluation of imaging criteria for neuronal migration disorders.
Highlights the importance of integrating clinical presentation with imaging findings for accurate diagnosis.