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Keratocystic odontogenic tumors related to Gorlin-Goltz syndrome: A clinicopathological study
Mohammed Israr Ul Khaliq1, Ajaz A Shah2, Irshad Ahmad3
1Post Graduate Scholar, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
Background:
Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin-Goltz syndrome in our institution from 2004 to 2015.
Method:
After histopathological analyses of KCOT related to Gorlin-Goltz syndrome, 7 patients were assessed. These patients presented a total of 15 primary and 2 recurrent KCOT.
Results:
All patients presented a multiple KCOT, and 13 lesions were located in mandible (77%) and 4 (23%) in maxilla. Most of the tumors presented a unilocular pattern (71%) and had tooth association (88%). Four patients (57%) were in the age group of 10-19 years and three patients (43%) were in the age group of 20-29 years. There were four male and three female patients.
Conclusion:
KCOT is a frequent manifestation of Gorlin-Goltz syndrome and can be its first sign, mainly in young patients. The four patients presented with two lesions (57%) and three lesions in three patients (43%).
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