Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Osmoregulation in Fishes

Osmoregulation in Fishes

When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?

Fixed Action Patterns

Fixed Action Patterns

A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CRISPuRe-seq: pooled screening of barcoded ribonucleoprotein reporters reveals regulation of RNA polymerase III transcription by the integrated stress response via mTOR.

Nucleic acids research·2025

Same author

CRISPuRe-seq: pooled screening of barcoded ribonucleoprotein reporters reveals regulation of RNA polymerase III transcription by the integrated stress response via mTOR.

Nucleic acids research·2025

Same author

A genome-wide atlas of human cell morphology.

Nature methods·2025

Same author

Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption.

eLife·2024

Same author

A genome-wide atlas of human cell morphology.

bioRxiv : the preprint server for biology·2023

Same author

The microtubule regulator <i>ringer</i> functions downstream from the RNA repair/splicing pathway to promote axon regeneration.

Genes & development·2020

Same journal

The exquisite mechanics of a tsetse bite.

eLife·2026

Same journal

Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.

eLife·2026

Same journal

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation.

eLife·2026

Same journal

Restraint of melanoma progression by cells in the local skin environment.

eLife·2026

Same journal

Brawn before bite in endemic Asian eutherian mammals after the end-Cretaceous extinction.

eLife·2026

Same journal

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 21, 2026

Modeling the Size Spectrum for Macroinvertebrates and Fishes in Stream Ecosystems

Modeling the Size Spectrum for Macroinvertebrates and Fishes in Stream Ecosystems

Published on: July 30, 2019

Finding FISH in a small pond.

¹Calico Life Sciences LLC, South San Francisco, United States.

|May 21, 2016

Summary

This summary is machine-generated.

Bacteria precisely position messenger RNAs (mRNAs) within their cells, mirroring complex eukaryotic mechanisms. This discovery highlights conserved gene regulation strategies across life forms.

Keywords:

E. coli RNA degradation biophysics cell biology fluorescence in situ hybridization next-generation sequencing spatial organization structural biology superresolution microscopy transcriptome

More Related Videos

Basic Methods for the Study of Reproductive Ecology of Fish in Aquaria

Basic Methods for the Study of Reproductive Ecology of Fish in Aquaria

Published on: July 20, 2017

Swimming Performance Assessment in Fishes

Swimming Performance Assessment in Fishes

Published on: May 20, 2011

Related Experiment Videos

Last Updated: Mar 21, 2026

Modeling the Size Spectrum for Macroinvertebrates and Fishes in Stream Ecosystems

Modeling the Size Spectrum for Macroinvertebrates and Fishes in Stream Ecosystems

Published on: July 30, 2019

Basic Methods for the Study of Reproductive Ecology of Fish in Aquaria

Basic Methods for the Study of Reproductive Ecology of Fish in Aquaria

Published on: July 20, 2017

Swimming Performance Assessment in Fishes

Swimming Performance Assessment in Fishes

Published on: May 20, 2011

Area of Science:

Microbiology
Molecular Biology
Cell Biology

Background:

Eukaryotic cells exhibit spatial control over gene expression through mRNA localization.
The mechanisms governing mRNA localization in prokaryotes remained largely uncharacterized.

Purpose of the Study:

To investigate whether bacteria also employ mRNA localization for spatial gene regulation.
To compare bacterial mRNA localization with eukaryotic strategies.

Main Methods:

Utilized advanced microscopy techniques, including super-resolution imaging.
Employed novel fluorescent labeling strategies for specific mRNA visualization.
Applied live-cell imaging to observe dynamic mRNA positioning in bacteria.

Main Results:

Demonstrated that bacterial mRNAs are not randomly distributed but are localized to specific subcellular regions.
Observed distinct localization patterns for different bacterial mRNAs, suggesting functional relevance.
Findings indicate a conserved principle of mRNA localization across prokaryotes and eukaryotes.

Conclusions:

Bacteria actively control mRNA localization, similar to eukaryotes.
This spatial mRNA organization likely plays a crucial role in bacterial physiology and gene expression.
The study reveals conserved mechanisms of post-transcriptional regulation in cellular organization.