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Autonomic dysfunction in primary sleep disorders.

Mitchell G Miglis1

  • 1Department of Neurology, Stanford University, 211 Quarry Rd, 2nd Floor, M/C 5992, Stanford, CA 94305, USA.

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|May 21, 2016
PubMed
Summary

The autonomic nervous system is crucial for sleep physiology. Untreated sleep disorders often present with autonomic impairment, highlighting a significant connection between these conditions.

Keywords:
AutonomicInsomniaNarcolepsyObstructive sleep apneaRestless legs syndromeSleep

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Area of Science:

  • Physiology
  • Neurology
  • Sleep Medicine

Background:

  • The autonomic nervous system regulates vital physiologic functions during sleep.
  • A bidirectional relationship exists between sleep disorders and autonomic dysfunction.
  • Many patients with sleep disorders exhibit autonomic symptoms, and vice versa.

Purpose of the Study:

  • To explore the link between autonomic nervous system impairment and sleep disorders.
  • To review existing literature on autonomic dysfunction in primary sleep disorders.

Main Methods:

  • Literature review of studies investigating autonomic function in sleep disorders.
  • Analysis of the physiological interplay between sleep and autonomic regulation.

Main Results:

  • Common sleep disorders are frequently associated with autonomic nervous system impairment.
  • Specific sleep disorders discussed include obstructive sleep apnea, insomnia, restless legs syndrome, periodic limb movement disorder, narcolepsy, and REM sleep behavior disorder.

Conclusions:

  • A strong association exists between autonomic nervous system dysfunction and primary sleep disorders.
  • Further research is warranted to elucidate the mechanisms underlying this connection and inform clinical practice.