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Solitary brain metastasis from prostate cancer: a case report
Tasneem Barakat1, Arnav Agarwal1, Rachel McDonald1
1Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Abstract:
Brain metastases arising from prostate cancer are exceedingly rare and typically occur late in the course of the disease. Most patients have widespread metastatic disease before developing brain metastases from prostate cancer. We report the case of a 67-year-old male with prostate cancer presenting with an isolated symptomatic brain metastasis. Aggressive treatment of the metastatic site included tumor resection and adjuvant stereotactic radiation treatment (RT) to the surgical bed, resulting in a favorable outcome.
Insights
Brain metastases from prostate cancer are rare, usually appearing late in the disease. This case highlights successful treatment of an isolated brain metastasis with surgery and stereotactic radiation treatment (RT).
Area of Science:
- Neuro-oncology
- Urologic Oncology
Background:
- Prostate cancer rarely metastasizes to the brain, typically occurring late in advanced disease stages.
- Widespread metastatic disease often precedes the development of brain metastases in prostate cancer patients.
Observation:
- A 67-year-old male with prostate cancer presented with a single, symptomatic brain metastasis.
- This presentation is unusual given the typical late-stage and widespread nature of prostate cancer metastasis.
Findings:
- The patient underwent aggressive treatment including surgical resection of the isolated brain metastasis.
- Adjuvant stereotactic radiation treatment (RT) was administered to the surgical bed.
Implications:
- Aggressive local treatment of isolated brain metastases in prostate cancer can lead to favorable outcomes.
- This case suggests that even rare presentations of prostate cancer metastasis warrant consideration for targeted therapeutic interventions.
