Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cytomegalovirus Disease01:27

Cytomegalovirus Disease

5
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
5
Human Virome01:26

Human Virome

4
The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible...
4

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From unlabeled to labeled: self-supervised deep learning in computational pathology.

BioData mining·2026
Same author

Chemical exposure and hepatic steatosis: How environmental factors impact liver health.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2026
Same author

Combined effects of heavy metals and volatile organic compounds on oxidative stress and cardiovascular risk.

American heart journal plus : cardiology research and practice·2026
Same author

Computational pathology with dynamic convolutional and adaptive kernels.

Journal of pathology informatics·2026
Same author

Enteric Viral Pathogens in Infants in the United States: 2017-2020.

Pediatrics·2026
Same author

Relative efficacy, safety, and immunogenicity analysis of two doses versus one dose of recombinant coronavirus vaccine (adenovirus type 5 vector) in adults 18 years and older: an international, multicentre, randomized, double blinded phase 3 trial.

Vaccine·2026

Related Experiment Video

Updated: Mar 21, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

20.6K

Fecal Polyomavirus Excretion in Infancy.

John A Vanchiere1, Berenice Carillo2, Ardythe L Morrow3

  • 1Department of Pediatrics, Section of Infectious Diseases Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas.

Journal of the Pediatric Infectious Diseases Society
|May 21, 2016
PubMed
Summary

Polyomaviruses like BK virus and JC virus are common in infants. Fecal samples revealed polyomavirus shedding in a significant percentage of 1-year-olds, suggesting the gut may harbor these viruses.

Keywords:
BK virusinfancypolyomavirus

More Related Videos

Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
11:54

Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry

Published on: July 13, 2019

9.4K
Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

10.5K

Related Experiment Videos

Last Updated: Mar 21, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

20.6K
Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
11:54

Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry

Published on: July 13, 2019

9.4K
Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

10.5K

Area of Science:

  • Virology
  • Human Microbiome Research
  • Pediatric Infectious Diseases

Background:

  • Polyomaviruses are a group of DNA viruses known to infect humans.
  • While some polyomaviruses cause disease, many establish persistent, asymptomatic infections.
  • The early life shedding patterns and persistence sites of common human polyomaviruses remain incompletely understood.

Purpose of the Study:

  • To investigate the prevalence of fecal polyomavirus shedding in 1-year-old infants.
  • To determine the frequency of specific polyomaviruses, including BK virus, JC virus, and simian virus 40, in this age group.
  • To explore the gastrointestinal tract as a potential site for polyomavirus persistence during early childhood.

Main Methods:

  • Utilized qualitative polymerase chain reaction (PCR) for sensitive detection of viral DNA.
  • Analyzed fecal specimens collected from a cohort of 1-year-old infants.
  • Quantified the percentage of positive specimens and the proportion of infants shedding polyomaviruses.

Main Results:

  • Polyomavirus DNA was detected in 17.8% of the 321 analyzed fecal specimens.
  • A substantial proportion, 64.1% of the 39 infants, had at least one polyomavirus-positive specimen.
  • BK virus, JC virus, and simian virus 40 were the targeted polyomaviruses in the fecal samples.

Conclusions:

  • The high prevalence of polyomavirus detection in infant feces indicates common exposure and shedding early in life.
  • These findings support the hypothesis that the human gastrointestinal tract serves as a significant site for polyomavirus persistence.
  • Further research is warranted to understand the long-term implications of early-life polyomavirus gastrointestinal colonization.