Related Experiment Video

Updated: Mar 20, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

5.5K

Brucella Septic Arthritis: Case Reports and Review of the Literature

Fatehi Elnour Elzein1, Nisreen Sherbeeni1

  • 1Division of Infectious Diseases, Department of Medicine, Prince Sultan Military Medical City (PSMMC), Riyadh 11159, Saudi Arabia.

Case Reports in Infectious Diseases
|May 21, 2016
PubMed

Insights

Brucellosis, a common zoonotic disease, frequently affects bones and joints, particularly in endemic regions like Saudi Arabia. Early suspicion is crucial for diagnosing septic arthritis, even with co-infections.

Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Public Health

Background:

  • Brucellosis is a prevalent zoonotic infection globally, endemic in regions including Saudi Arabia, the Middle East, and the Mediterranean.
  • Osteoarticular involvement is a common clinical presentation of brucellosis.
  • While sacroiliac joint involvement is typical, spondylitis and peripheral arthritis are increasingly recognized manifestations.

Purpose of the Study:

  • To highlight the significance of osteoarticular manifestations in brucellosis.
  • To emphasize the potential for brucellosis to be misdiagnosed, especially with co-infections.
  • To advocate for increased suspicion of brucellosis in septic arthritis cases within endemic areas.

Main Methods:

  • Review of clinical presentations of brucellosis with a focus on musculoskeletal involvement.
  • Analysis of epidemiological data from endemic regions.
  • Discussion of diagnostic challenges, including co-infections.

Main Results:

  • Osteoarticular involvement, including sacroiliitis, spondylitis, and peripheral arthritis, is a frequent complication of brucellosis.
  • Brucellosis can be easily overlooked in patients presenting with septic arthritis, particularly if other bacteria are present.
  • Geographical location and travel history are critical factors in suspecting brucellosis.

Conclusions:

  • Brucellosis should be strongly considered in the differential diagnosis of septic arthritis, especially in endemic zones or among travelers.
  • Increased awareness and diagnostic vigilance are necessary to prevent delayed or missed diagnoses of brucellosis-related osteoarticular complications.
  • Prompt diagnosis and treatment are essential for managing brucellosis and its musculoskeletal sequelae.

More Related Videos

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.6K
Knee Arthrocentesis in Adults04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

10.2K

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
606
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.0K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
16.5K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
953
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
1.1K