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Updated: Mar 20, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
A comparative study of bifidobacteria in human babies and adults
Shadi Khonsari1, Mayuran Suganthy1, Beata Burczynska1
1School of Science and Technology, Middlesex University, Town Hall The Burroughs, Hendon, London NW4 4BT, UK.
Insights
Bifidobacteria levels are significantly higher in babies compared to adults. Factors like diet, age, and BMI influence bifidobacteria in adults, while diet and age are key in babies.
Area of Science:
- Microbiology
- Human Gut Microbiome
- Pediatric Health
Background:
- Gut microbiota composition differs significantly between infants and adults.
- Bifidobacteria are a key genus in the infant gut microbiome.
- Understanding factors influencing Bifidobacteria levels is crucial for gut health.
Purpose of the Study:
- To compare Bifidobacteria levels in babies and adults.
- To investigate the impact of lifestyle factors on Bifidobacteria abundance.
- To identify age-specific influences on intestinal Bifidobacteria.
Main Methods:
- Comparative analysis of Bifidobacteria levels.
- Study included 10 human infants (<2 years) and 10 adults (>40 years).
- Assessment of lifestyle factors including diet and Body Mass Index (BMI).
Main Results:
- Significantly higher levels of Bifidobacteria were observed in babies compared to adults.
- In adults, age, diet, and BMI collectively influenced Bifidobacteria levels.
- In infants, diet and age were identified as potential key influencers of Bifidobacteria.
Conclusions:
- Infant gut microbiota, particularly Bifidobacteria, differs markedly from adults.
- Lifestyle factors play a significant role in modulating adult gut Bifidobacteria.
- Age and diet are critical determinants of Bifidobacteria levels in both infants and adults.
Abstract:
The composition and diversity of the gut microbiota are known to be different between babies and adults. The aim of this project was to compare the level of bifidobacteria between babies and adults and to investigate the influence of lifestyle factors on the level of this bacterium in the gut. During this study, the levels of bifidobacteria in 10 human babies below 2 years of age were compared with that of 10 human adults above 40 years. The level of bifidobacteria proved to be significantly higher in babies in comparison with adults. This investigation concluded that a combination of several factors, such as age, diet, and BMI, has an important effect on the level of bifidobacteria in adults, while in babies, a combination of diet and age may influence the level of intestinal bifidobacteria.
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