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Published on: December 3, 2012
Asynchronous Detected Disappearance of the Pro-nuclei by Time-Lapse X Embryonic Development
Guilherme Rios Franco Rosário1, Antônio Carlos Costa Franco1, Adriana Valério da Silva1
1Embryolife Instituto de Medicina Reprodutiva, São José dos Campos/SP.
Objective:
To investigate whether pro-nuclei disappearance synchronicity would have something to do with blastomere cleavage time up to D3 (timeline) and if it would be associated with the appearance of embryo abnormalities.
Methods:
The sample of the present study was designed with 100 embryos (n = 100). With the aid of an embryonic analysis equipment: Time-Lapse, we studied embryonic morphokinetics from the zygote stage to D3.
Results:
When there was no pronuclei synchronous disappearance, 30.8% underwent normal cleavage, whereas when there was pronuclei synchronous disappearance, 44.8% had normal cleavage. When there was no pronuclei synchronous disappearance, 46.2% had some type of abnormality, whereas when there was pronuclei synchronous disappearance, 56.3% had some kind of abnormality.
Conclusion:
Although the statistical results were not significant, we believe that with a larger sample size we could state with higher reliability, that the pro-nuclei synchronous disappearance analysis may, in the near future, indicate higher embryo quality.
