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Updated: Mar 20, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Increased overall drug utilization in patients with psoriasis: a case-control study based on Dutch general
E A Dowlatshahi1, L M Hollestein1, R M C Herings2
1Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands.
The British Journal of Dermatology
|May 21, 2016
Summary
Patients with psoriasis use more medications overall compared to those without the condition. This increased drug utilization, even for unrelated conditions, highlights higher healthcare needs in psoriasis patients.
Area of Science:
- Dermatology
- Pharmacology
- Health Services Research
Background:
- Psoriasis medication use research has primarily focused on comorbidities.
- Detailed drug utilization patterns in psoriasis patients remain underexplored.
Purpose of the Study:
- To compare detailed drug utilization between patients with psoriasis and matched controls.
- To analyze prescription data from a large, population-based sample.
Main Methods:
- A case-control study utilizing a Dutch general practitioner database (2002-2012).
- 17,627 patients with psoriasis were matched 1:1 with controls.
- Mantel-Haenszel odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.
Main Results:
- Patients with psoriasis received significantly more unique drugs (mean 9) than controls (mean 7).
- Increased prescription rates were observed for psoriasis treatments, comorbidities, and even unrelated medications like nasal preparations and laxatives.
- 20% of psoriasis patients received no specific psoriasis treatment, and 8% had moderate-to-severe disease.
Conclusions:
- Psoriasis patients exhibit higher overall drug prescription rates across all categories, irrespective of comorbidities.
- This suggests increased healthcare utilization among individuals with psoriasis.
- Routine database analysis reveals significant differences in medication patterns.
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