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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Related Experiment Video

Updated: Mar 20, 2026

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Bacterial Cholangitis, Cholecystitis, or both in Dogs.

A Tamborini1, H Jahns1, H McAllister1

  • 1School of Veterinary Medicine, University College Dublin, Dublin, Ireland.

Journal of Veterinary Internal Medicine
|May 21, 2016
PubMed
Summary
This summary is machine-generated.

Bacterial cholangitis and cholecystitis in dogs are more common than previously thought. Early identification and treatment are crucial for managing these serious liver and gallbladder conditions in canine patients.

Keywords:
CanineCholangiohepatitisHepatitisLiver disease

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Area of Science:

  • Veterinary Medicine
  • Canine Hepatobiliary Diseases
  • Infectious Diseases

Background:

  • Bacterial cholangitis and cholecystitis are uncommon and poorly understood canine diseases.
  • This study aimed to define the clinical characteristics of these conditions in dogs.

Purpose of the Study:

  • To characterize the clinical features of bacterial cholangitis and cholecystitis in dogs.
  • To identify common bacterial isolates and their antimicrobial resistance patterns.
  • To assess outcomes and prognosis for affected dogs.

Main Methods:

  • A retrospective case series of 27 dogs with histopathologically confirmed bacterial cholangitis, cholecystitis, or both.
  • Data collected from January 2000 to June 2011 across four veterinary schools.
  • Included analysis of clinical pathology, ultrasonography, bile culture, and bacterial isolates.

Main Results:

  • Common findings included elevated liver enzymes, hyperbilirubinemia, and inflammatory leukograms.
  • Escherichia coli was the most frequent isolate, with significant antimicrobial resistance noted.
  • Biliary tract rupture occurred in nearly one-third of cases, associated with high mortality.

Conclusions:

  • Bacterial cholangitis and cholecystitis are more prevalent in dogs than literature suggests.
  • These conditions should be considered in dogs with jaundice, fever, abdominal pain, or gallbladder abnormalities.
  • Prognosis is guarded to fair, with potential for persistent liver enzyme elevation.