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Bacterial Cholangitis, Cholecystitis, or both in Dogs.
A Tamborini1, H Jahns1, H McAllister1
1School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Journal of Veterinary Internal Medicine
|May 21, 2016
Summary
Bacterial cholangitis and cholecystitis in dogs are more common than previously thought. Early identification and treatment are crucial for managing these serious liver and gallbladder conditions in canine patients.
Area of Science:
- Veterinary Medicine
- Canine Hepatobiliary Diseases
- Infectious Diseases
Background:
- Bacterial cholangitis and cholecystitis are uncommon and poorly understood canine diseases.
- This study aimed to define the clinical characteristics of these conditions in dogs.
Purpose of the Study:
- To characterize the clinical features of bacterial cholangitis and cholecystitis in dogs.
- To identify common bacterial isolates and their antimicrobial resistance patterns.
- To assess outcomes and prognosis for affected dogs.
Main Methods:
- A retrospective case series of 27 dogs with histopathologically confirmed bacterial cholangitis, cholecystitis, or both.
- Data collected from January 2000 to June 2011 across four veterinary schools.
- Included analysis of clinical pathology, ultrasonography, bile culture, and bacterial isolates.
Main Results:
- Common findings included elevated liver enzymes, hyperbilirubinemia, and inflammatory leukograms.
- Escherichia coli was the most frequent isolate, with significant antimicrobial resistance noted.
- Biliary tract rupture occurred in nearly one-third of cases, associated with high mortality.
Conclusions:
- Bacterial cholangitis and cholecystitis are more prevalent in dogs than literature suggests.
- These conditions should be considered in dogs with jaundice, fever, abdominal pain, or gallbladder abnormalities.
- Prognosis is guarded to fair, with potential for persistent liver enzyme elevation.
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