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Prenatal Exposure to Perfluorinated Compounds Affects Birth Weight Through GSTM1 Polymorphism

Eun Jin Kwon1, Joon Soo Shin, Byung Mi Kim

  • 1Department of Preventive Medicine, School of Medicine, Ewha Womans University, Seoul, South Korea (Ms Kwon, Drs Kim, Kulkarni, Park, Ha); Department of Pediatrics, School of Medicine, Ewha Womans University, Seoul, South Korea (Dr Park); Department of Obstetrics and Gynecology, School of Medicine, Ewha Womans University, Seoul, South Korea (Ms Kwon, Dr Kim); Department of Health, Environment & Safety, Eulji University, Seongnam, South Korea (Dr Kho); Cancer Policy Branch (Dr Kim), National Cancer Center, Goyang, South Korea; and Chicago Medical School (Mr Shin), Rosalind Franklin University of Medicine and Science, Lake County, Illinois.

Journal of Occupational and Environmental Medicine
|May 21, 2016
PubMed
Summary

Prenatal exposure to perfluorinated compounds (PFCs) can reduce birth weight. Genetic variations, specifically glutathione S-transferase M1 (GSTM1) null genotype, may increase susceptibility to these effects.

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