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Updated: Mar 20, 2026

Candida albicans Biofilm Development on Medically-relevant Foreign Bodies in a Mouse Subcutaneous Model Followed by Bioluminescence Imaging
Published on: January 27, 2015
First report of macroscopic biofilm formation caused by Candida albicans on silver hydrogel-coated urinary catheters
Mehmet Burak Selek1, Tuğba Kula Atik1, Bayhan Bektöre1
1Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
Abstract:
We report macroscopic biofilms on silver hydrogel-coated urinary catheters in 2 patients from 2 different intensive care units. The catheters were removed on observation of a white, jelly layer on the catheters, respectively, 9 and 21 days after insertion. Yeast cells and pseudohyphal structures were observed with microscopy. Both isolates were identified as Candida albicans. To our knowledge, these are the first cases demonstrating the formation of macroscopic biofilm layers on silver nitrate-coated catheters in the literature.

