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Graphene Quantum Dots for Theranostics and Bioimaging.

Kathryn L Schroeder1, Renee V Goreham1, Thomas Nann2

  • 1The MacDiarmid Institute for Advanced Materials & Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, PO Box 600, Wellington, Wellington, 6140, New Zealand.

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Graphene quantum dots (GQDs) show great potential for biomedical applications like disease detection and drug delivery. Many GQDs exhibit low toxicity, making them promising for advanced health technologies.

Keywords:
bioimagingdrug deliverygraphene quantum dotstoxicity

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Area of Science:

  • Biomedical Science
  • Nanotechnology
  • Materials Science

Background:

  • Nanomaterials offer advanced biomedical technology potential since the 1990s.
  • Graphene quantum dots (GQDs) are emerging nanomaterials with significant biomedical promise.
  • Applications include bioimaging, drug delivery, and disease biomarker sensors.

Purpose of the Study:

  • To critically review and discuss the current applications of GQDs in biology and health sciences.
  • To highlight the versatility of GQDs as targeted multimodal treatment and imaging platforms.
  • To explore the in vitro and in vivo toxicity profiles of various GQDs.

Main Methods:

  • Literature review of state-of-the-art GQD applications.
  • Analysis of GQD functionalization for targeted therapies.
  • Evaluation of GQD toxicity studies.

Main Results:

  • GQDs can be easily functionalized for targeted multimodal treatment and imaging.
  • GQDs demonstrate potential for improving bioimaging, drug delivery, and disease biomarker sensing.
  • Many types of GQDs exhibit low in vitro and in vivo toxicity.

Conclusions:

  • Graphene quantum dots represent a promising class of nanomaterials for diverse biomedical applications.
  • Their low toxicity and functionalizability support their development for targeted therapies and diagnostics.
  • Further research into GQD applications can advance early disease detection and treatment strategies.