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Updated: Mar 20, 2026

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
Published on: February 2, 2024
Altitude Decompression Sickness Risk and Physical Activity During Exposure.
James T Webb1, Thomas R Morgan, Sean D Sarsfield
1Wyle Laboratories, San Antonio, TX, USA.
Low physical activity during high-altitude exposure, like in seated, nonambulatory conditions, shows no incidence of decompression sickness (DCS). This confirms a strong linear relationship between activity level and DCS risk, potentially refining altitude safety protocols.
Area of Science:
- Aerospace Medicine
- Physiology
- High-Altitude Research
Background:
- Previous studies identified a linear link between peak oxygen consumption (Vo2) and decompression sickness (DCS) incidence at high altitudes.
- The current study investigated if this relationship persists at a lower altitude exposure.
Purpose of the Study:
- To determine if the established linear relationship between oxygen consumption and DCS incidence holds true at a lower altitude.
- To assess DCS risk in subjects exposed to 22,500 ft while seated and nonambulatory.
Main Methods:
- Twenty male subjects were exposed to 22,500 ft (6.1 psi) for 4 hours breathing 100% oxygen.
- Subjects remained seated and nonambulatory throughout the exposure, with intermittent echo-imaging.
- Peak 1-minute oxygen consumption (Vo2) and activity levels were recorded and compared to prior research with higher activity levels.
Main Results:
- No cases of decompression sickness (DCS) or venous gas emboli were observed in any subjects.
- A strong linear relationship (r > 0.99) was confirmed between DCS incidence and the level of physical activity, consistent with previous findings.
Conclusions:
- Findings suggest that physiological safety margins may be extended or pre-breathing time reduced for high-altitude operations with minimal physical activity.
- The results may help explain differential DCS risk between observers and trainees in altitude chambers.
- Quantified activity levels could enhance current altitude DCS risk prediction models.
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