Related Experiment Video
Updated: Mar 20, 2026
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Image guided surgery in the management of head and neck cancer
1Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Abstract:
Complete resection of head and neck tumors relies on palpation and visual inspection. Achieving a negative margin in remote locations in the head and neck region, especially in close proximity to critical structures, is often difficult to achieve. Positive resection margins in head and neck cancer are at high risk to develop recurrent disease and associated with poor prognosis. Near-infrared fluorescence-guided optical imaging is an emerging technology with the potential to move the surgical field forward and facilitate surgeons to visualize tumors in real-time intra-operatively. In this review, our focus is to discuss the recent advances and the potential application of near infrared (NIR) fluorescent-guided surgery in the management of head and neck cancer.
Insights
Near-infrared fluorescence-guided surgery helps surgeons visualize tumors during head and neck cancer operations. This technology aims to improve complete tumor resection and patient outcomes by enabling real-time intra-operative visualization.
Area of Science:
- Oncology
- Surgical Technology
- Medical Imaging
Background:
- Complete resection of head and neck tumors is challenging due to reliance on visual inspection and palpation.
- Positive resection margins in head and neck cancer correlate with high recurrence rates and poor prognosis.
- Accurate margin assessment is critical for improving patient outcomes in head and neck cancer surgery.
Purpose of the Study:
- To review recent advances in near-infrared (NIR) fluorescence-guided optical imaging for head and neck cancer.
- To discuss the potential applications of NIR fluorescence imaging in improving surgical management of head and neck tumors.
- To highlight how real-time intra-operative visualization can enhance surgical precision.
Main Methods:
- Review of current literature on NIR fluorescence-guided surgery in head and neck oncology.
- Analysis of technological advancements in NIR fluorescent agents and imaging systems.
- Discussion of clinical applications and potential benefits in surgical decision-making.
Main Results:
- NIR fluorescence-guided surgery offers real-time visualization of tumor boundaries, even in difficult-to-reach areas.
- The technology has the potential to improve the accuracy of tumor resection and reduce positive margin rates.
- Emerging NIR agents and imaging devices show promise for enhanced intra-operative guidance.
Conclusions:
- Near-infrared fluorescence-guided surgery represents a significant advancement in head and neck cancer management.
- This technology can assist surgeons in achieving complete tumor resection by providing real-time visual feedback.
- Further research and clinical integration of NIR fluorescence imaging are expected to improve surgical outcomes for head and neck cancer patients.
