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Updated: Mar 20, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
[Keloid scars (part II): Treatment and prevention]
C Jaloux1, B Bertrand1, N Degardin1
1Service de chirurgie plastique et réparatrice, centre hospitalo-universitaire de Marseille, hôpital Nord, AP-HM, chemin des Bourrely, 13915 Marseille cedex 20, France.
Keloid scars result from abnormal wound healing and often recur after surgical removal. This study proposes a management strategy combining treatment and long-term follow-up to address keloid scar recurrence.
Area of Science:
- Dermatology
- Wound Healing Research
- Surgical Pathology
Background:
- Keloid scars represent a disordered cutaneous wound healing response.
- These scars cause significant physical and psychological distress.
- Recurrence is common, even after surgical excision.
Purpose of the Study:
- To propose a comprehensive management strategy for keloid scars.
- To address the challenge of keloid scar recurrence.
- To provide guidance for long-term keloid scar management.
Main Methods:
- Literature review on keloid scar pathogenesis and treatments.
- Development of a multi-faceted management approach.
- Emphasis on integrated treatment and follow-up protocols.
Main Results:
- Current treatments for keloid scars are numerous but not ideal.
- No single treatment guarantees complete eradication.
- Effective keloid scar management requires a strategic, long-term approach.
Conclusions:
- Keloid scar management necessitates a combination of therapeutic interventions.
- Long-term follow-up is crucial for monitoring and managing recurrence.
- The proposed strategy aims to improve patient outcomes for keloid scars.
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