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Elastase 1 and chymotrypsin B in pancreatic juice and feces
A Sziegoleit1, E Krause, H U Klör
1Department of Gastroenterology, University of Giessen, FRG.
Clinical Biochemistry
|April 1, 1989
Abstract:
A chymotrypsin-like protease was detected along with elastase 1 in pancreatic secretion and stool. This enzyme was isolated from necrobiotic human pancreas, purified, partially characterized and designated as chymotrypsin B. Quantitative studies by rocket immunoelectrophoresis indicated that neither elastase 1 nor chymotrypsin B was degraded during intestinal passage. On the basis of a clinical study, both enzymes were found to reflect pancreatic function.