Self-reported gadolinium toxicity: A survey of patients with chronic symptoms
Lauren M B Burke1, Miguel Ramalho1, Mamdoh AlObaidy1
1Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Purpose:
This study aims to describe the self-reporting symptoms experienced by individuals with self-reported normal renal function after gadolinium based contrast agent (GBCA) administration.
Materials And Methods:
This HIPAA-compliant, IRB-approved study consisted of an anonymous online survey of patients who believe that they suffer from gadolinium toxicity. 50 respondents completed the nine-question survey.
Results:
Fifty (100%) of the subjects ascribed their complaints to gadolinium exposure. Thirty-three (66%) described the onset immediately following GBCA administration and 16 (32%) within 6weeks. The most common symptoms included bone/joint pain and head/neck symptoms including headache, vision change, and hearing change (77.6% each). Other symptoms occurred with lesser incidence.
Conclusions:
This survey represents an initial description of patients with normal renal function who self-described toxicity related to GBCA administration. Bone and joint complaints and skin changes are two of the most common complaints.
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