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Ultraviolet A1 phototherapy: One center's experience.
Sasi Kiran Attili1, Robert S Dawe2, Sally H Ibbotson2
1Department of Dermatology and Photobiology, Ninewells University Hospital, Dundee, DD1 9SY, Scotland, UK; Visakha Institute of Skin and Allergy, Visakhapatnam, Andhra Pradesh, India.
Summary
Ultraviolet A1 (UVA1) phototherapy shows promise for treating various skin conditions like atopic dermatitis and morphea. This retrospective review found UVA1 phototherapy to be beneficial and well-tolerated in selected dermatoses.
Area of Science:
- Dermatology
- Phototherapy
- Medical Treatments
Background:
- Ultraviolet A1 (UVA1) phototherapy is gaining traction for treating recalcitrant dermatoses.
- Conditions treated include morphea, atopic dermatitis, lupus, and others.
- This study presents a retrospective review of UVA1 phototherapy experiences.
Purpose of the Study:
- To assess treatment response rates for various dermatoses using UVA1 phototherapy.
- To evaluate adverse effects associated with UVA1 phototherapy.
Main Methods:
- Retrospective review of phototherapy notes and patient records.
- Data collected from October 1996 to December 2008.
- Analysis of treatment courses and outcomes for 269 patients.
Main Results:
- Beneficial outcomes observed in atopic dermatitis (53%) and morphea (51%).
- High efficacy noted in urticaria (100%) and polymorphic light eruption (85.7%).
- Treatment was generally well-tolerated with no treatment-related discontinuations.
Conclusions:
- UVA1 phototherapy is a viable option for selected dermatoses.
- Further research is needed to understand long-term risks, such as malignancy.
- The study is limited by its retrospective nature and potential for bias.
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