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[The post-streptococcal diseases in the clinical practice]
A V Aksenova1, N A Shostak1, O A Guseva1
1N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
Insights
This study details streptococcal infections, covering clinical forms, pathogenesis, and diagnosis. It also assesses the risk of post-streptococcal diseases in children and proposes prevention strategies.
Area of Science:
- Microbiology
- Infectious Diseases
- Pediatrics
Context:
- Streptococcal infections represent a significant global health concern, particularly in pediatric populations.
- Understanding the diverse clinical manifestations and pathogenesis is crucial for effective management.
- Current diagnostic approaches and the risk of sequelae require thorough evaluation.
Purpose:
- To comprehensively review the clinical spectrum and pathogenesis of streptococcal infections.
- To outline modern laboratory diagnostic methods for these infections.
- To evaluate the risk of developing post-streptococcal sequelae in children and propose preventive measures.
Summary:
- The review covers various clinical forms of streptococcal infections, their underlying pathogenetic mechanisms, and characteristic clinical presentations.
- It discusses contemporary laboratory diagnostic techniques for identifying streptococcal pathogens.
- The authors assess the likelihood of children developing post-streptococcal diseases and suggest preventative interventions.
Impact:
- Provides a consolidated resource for clinicians and researchers on streptococcal infections.
- Highlights advancements in laboratory diagnostics for improved early detection.
- Offers insights into risk assessment and prevention of serious sequelae in pediatric patients.
Abstract:
The authors describe various clinical forms of streptococcal infections, the pathogenetic mechanisms underlying these conditions, and peculiarities of their clinical picture. Also considered are the modern methods employed for laboratory diagnostics of streptococcal infections. The probability of the risk of development of post-streptococcal diseases in the children is evaluated. Measures for the prevention of these conditions are proposed.
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