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Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Long-term survival of HIV-infected patients with haemophilia
N Stieltjes1, Y Sultan1, C Rothschild1
1Centre des Hémophiles, Hǒpital Cochin, Paris; Centre des Hémophiles, Hǒpital Necker, Paris; Centre des Hémophiles, Hǒpital Bicětre, Paris; Maladies du Sang, Hǒpital Lapeyronic, Montpellier; Centre de Transfusion Sanguine, Angers; Centre de Transfusion Sanguine, Lille; Centre Rey Leroux, La Bouexière, Rennes, France.
Abstract:
In France, patients with haemophilia were infected by HIV up until October 1985, with a maximum of seroconversion between 1983 and 1985. There was a progressive development of AIDS in the 1158 infected patients as reported by Health Authorities. By the end of 1992, 32% of the haemophilia population had developed AIDS and 38 had developed clinical or biological symptoms of immunodeficiency. However, 27% had no clinical symptoms and no severe disorder of the immune system. The present study was established to determine factors common to patients with prolonged survival.
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