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Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
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Optimizing safety and accuracy of prostate biopsy
Tonye A Jones1, Jan Phillip Radtke, Boris Hadaschik
1aDepartment of Urology, David Geffen School of Medicine, Los Angeles, California, USA bDepartment of Urology, Heidelberg University Hospital, Heidelberg, Germany.
Current Opinion in Urology
|May 24, 2016
Summary
Prostate biopsy is safe, with infectious complications minimized by antibiotic resistance monitoring. MRI-ultrasound fusion enhances prostate cancer detection accuracy and reduces false negatives.
Area of Science:
- Urology
- Medical Imaging
- Oncology
Background:
- Prostate biopsy is a common procedure for diagnosing prostate cancer.
- Potential complications include hematospermia, hematuria, and infection, with growing concern over quinolone-resistant bacteria.
- Multiparametric MRI (mpMRI) aids in visualizing cancerous areas within the prostate.
Purpose of the Study:
- To evaluate the safety profile of prostate biopsy procedures.
- To explore the role of MRI-ultrasound fusion technology in enhancing diagnostic accuracy for prostate cancer.
Main Methods:
- Review of current practices in prostate biopsy, including infection prevention strategies.
- Description of MRI-ultrasound fusion technique for guiding prostate biopsies.
- Analysis of diagnostic outcomes comparing traditional methods with fusion technology.
Main Results:
- Prostate biopsy is generally safe, and infectious complications can be mitigated through appropriate antibiotic prophylaxis and surgical approaches like transperineal access.
- MRI-ultrasound fusion enables precise targeting of suspicious lesions identified on mpMRI.
- This fusion technique has led to increased detection rates of clinically significant prostate cancer and a reduction in biopsy under-sampling.
Conclusions:
- Prostate biopsy safety is maintained with careful attention to antibiotic resistance patterns.
- MRI-ultrasound fusion represents a significant advancement, improving biopsy accuracy and targeting capabilities.
- The technology enhances the ability to diagnose prostate cancer more effectively.
