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Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
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[MEDICAL CANNABIS].

Timna Naftali

    Harefuah
    |May 25, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Cannabis shows potential for pain and inflammation but has side effects. Medical cannabis use should be limited to patients who have not responded to established treatments.

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    Area of Science:

    • Pharmacology
    • Pain Management
    • Inflammatory Diseases

    Context:

    • Cannabis has a long history of medicinal use for pain, diarrhea, and inflammation.
    • Current research explores its efficacy in conditions like multiple sclerosis, epilepsy, dystonia, and chronic pain.
    • Cannabinoids demonstrate potential in managing pain in rheumatoid arthritis and Crohn's disease.

    Purpose:

    • To review the therapeutic potential of cannabis and cannabinoids.
    • To highlight the known side effects associated with cannabis use.
    • To provide guidance on the current appropriate use of medical cannabis.

    Summary:

    • Cannabis and its compounds, cannabinoids, are being investigated for various medical conditions, showing promise in managing pain and inflammation.
    • However, potential side effects such as psychosis, anxiety, and dependence are significant concerns.
    • The limited number and size of controlled clinical studies necessitate caution.

    Impact:

    • Cannabis offers potential therapeutic benefits for pain and inflammatory conditions.
    • The risks of side effects necessitate careful consideration and further research.
    • Current recommendations advise limiting medical cannabis to patients refractory to conventional therapies.