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Updated: Mar 20, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Melanoma of the Foot
1Faculty of Health Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Abstract:
Melanoma is a rare form of skin cancer that is responsible for most skin cancer deaths globally. Tumors arising on the foot continue to be a particular challenge. Patients present later and lesions are frequently misdiagnosed, leading to more advanced disease with an overall poorer prognosis then melanoma elsewhere. In order to improve early recognition, this article reviews the clinical features of the disease along with published algorithms. Emerging assessment techniques such as dermoscopy are also discussed as tools to improve clinical decision making. Contemporary drug therapies in the treatment of advanced disease are also discussed.
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