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GPR55: Metabolic Help or Hindrance?
Christopher M Henstridge1, Andrew J Brown2, Maria Waldhoer3
1Centre for Cognitive and Neural Systems, University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK.
Trends in Endocrinology and Metabolism: TEM
|May 25, 2016
Abstract:
Since the discovery of the lysophospholipid-sensitive receptor GPR55, hopes have been raised that targeting this G protein-coupled receptor (GPCR) may represent a novel approach for the treatment of metabolic disorders. We discuss conflicting evidence surrounding GPR55 physiology and highlight its potential as a novel target for the treatment of obesity and diabetes.
